The TPM® delivery systems have been shown to be suitable for delivering both small and large molecules up to 30,000 Daltons in size. Examples of the later successfully delivered to date include insulin (lispro and the hexamer).
TPM® delivery systems include:
1. Vesicular system - a multi-lamellar malleable vesicular carrier whose size can be tightly controlled. This allows TPM® to be formulated in a range of sizes, from nanometres to microns in diameter
2. Micro-emulsions - ointments and gels
3. Liquid - oral solutions
4. Patch systems - reservoir and think film matrix systems
TPM® transdermal delivery systems are:
- Easy to formulate
- Non - invasive
- User - friendly
- Anti-inflammatory and non-irritant
Additionally, the unique technology allows for the size of the vesicles to be controlled, the rate of diffusion through the skin (and as a result the systemic release rate) can also be controlled.